Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ESCO2 All Species: 12.42
Human Site: Y420 Identified Species: 34.17
UniProt: Q56NI9 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q56NI9 NP_001017420.1 601 68307 Y420 R F L E G I K Y V G W K K E R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_543224 598 67974 Y417 R F L E G I K Y T G W K K E R
Cat Felis silvestris
Mouse Mus musculus Q8CIB9 592 67255 E423 K F V G W K R E R V V A E F W
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508920 682 76075 F499 R F V E G I K F V G W K K E R
Chicken Gallus gallus XP_420012 679 73766 Y494 R F L E C L R Y V C W K K E R
Frog Xenopus laevis NP_001089603 640 69941 Y457 R L L E G I R Y V G W K K E R
Zebra Danio Brachydanio rerio Q5SPR8 609 68341 F425 R F L D T I K F V G W K K E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791750 838 93461 F658 K Y L S S I K F P G W K Q E E
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001146746 323 35496 G183 V T E P I K T G H R V I P S S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 74.2 N.A. 69 N.A. N.A. 45.8 37.4 36.7 37.4 N.A. N.A. N.A. N.A. 27.9
Protein Similarity: 100 N.A. N.A. 84.1 N.A. 80 N.A. N.A. 60.4 53.4 51.5 53.5 N.A. N.A. N.A. N.A. 43
P-Site Identity: 100 N.A. N.A. 93.3 N.A. 6.6 N.A. N.A. 86.6 73.3 86.6 80 N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 N.A. N.A. 93.3 N.A. 33.3 N.A. N.A. 100 86.6 93.3 93.3 N.A. N.A. N.A. N.A. 73.3
Percent
Protein Identity: N.A. 21.6 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 31.2 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 0 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 0 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % A
% Cys: 0 0 0 0 12 0 0 0 0 12 0 0 0 0 0 % C
% Asp: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 12 56 0 0 0 12 0 0 0 0 12 78 12 % E
% Phe: 0 67 0 0 0 0 0 34 0 0 0 0 0 12 0 % F
% Gly: 0 0 0 12 45 0 0 12 0 67 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 12 67 0 0 0 0 0 12 0 0 0 % I
% Lys: 23 0 0 0 0 23 56 0 0 0 0 78 67 0 0 % K
% Leu: 0 12 67 0 0 12 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 12 0 0 0 0 12 0 0 0 12 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % Q
% Arg: 67 0 0 0 0 0 34 0 12 12 0 0 0 0 67 % R
% Ser: 0 0 0 12 12 0 0 0 0 0 0 0 0 12 12 % S
% Thr: 0 12 0 0 12 0 12 0 12 0 0 0 0 0 0 % T
% Val: 12 0 23 0 0 0 0 0 56 12 23 0 0 0 0 % V
% Trp: 0 0 0 0 12 0 0 0 0 0 78 0 0 0 12 % W
% Tyr: 0 12 0 0 0 0 0 45 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _